Desmethylbellidifolin From Gentianella acuta Ameliorate TNBS-Induced Ulcerative Colitis Through Antispasmodic Effect and Anti-Inflammation

Effect on various organs in TNBS-induced ulcerative colitis

Purpose: In this study, the effect on heart, kidneys and liver organs in TNBS-induced Ulcerative colitis was investigated. Method: Twenty mice were randomly divided into two groups, which included normal group and model group. The model of chronic colitis was induced by 50% TNBS. The model of chronic colitis was verified by body weight, H&E staining. Heart, kidneys and liver organs were tested ...

Anti-inflammatory effect of Prunus armeniaca L. (Apricot) extracts ameliorates TNBS-induced ulcerative colitis in rats

Prunus armeniaca L. (Apricot) is a tree cultivated in different parts of the world. Apricot kernel as a good dietary supplement has shown antioxidant, anti-inflammatory and other pharmacologic properties which suggest that it may be functional as an anticolitis agent. In this study we evaluated the effects of apricot kernel extract and oil on ulcerative colitis in rats. Rats were fasted for 36 ...

anti-inflammatory effect of prunus armeniaca l. (apricot) extracts ameliorates tnbs-induced ulcerative colitis in rats

prunus armeniaca l. (apricot) is a tree cultivated in different parts of the world. apricot kernel as a good dietary supplement has shown antioxidant, anti-inflammatory and other pharmacologic properties which suggest that it may be functional as an anticolitis agent. in this study we evaluated the effects of apricot kernel extract and oil on ulcerative colitis in rats. rats were fasted for 36 ...

prunus armeniaca l. (apricot) two fractions ameliorate tnbs-induced ulcerative colitis in rats

Anti-inflammatory Effect of Amitriptyline on Ulcerative Colitis in Normal and Reserpine-Induced Depressed Rats

Depressive disorders are more common among persons with chronic diseases such as inflammatory bowel disease and anti-inflammatory effect of some antidepressants such as amitriptyline has been reported. Acetic acid colitis was induced in both reserpinised (depressed) and non-reserpinised (normal) rats. Reserpinised groups received reserpine (6 mg/kg, i.p.) one hour prior to colitis induction. Th...